- Search NCIBI Data
(e.g. diabetes, csf1r)
Addressing Grand Challenges with
Integrative Biomedical Informatics in Translational Settings
The National Center for Integrative Biomedical Informatics (NCIBI) was founded in October 2005 and is one of seven National Centers for Biomedical Computing (NCBC) in the NIH Roadmap. NCIBI is based at the University of Michigan as a part of the Center for Computational Medicine and Biology (CCMB). The Center develops conceptual models, computational infrastructure, an integrated knowledge repository, and query and analysis tools that enable scientists to effectively access and integrate the wealth of biological data.
About the Meeting
The first day of the 2009 Annual Research Meeting meeting featured a "Try our NCIBI Tools" workshop about NCIBI tools and applications followed by a keynote talk by Gwen Jacobs, Ph.D., Professor, Department of Cell Biology and Neuroscience, Montana State University.
The second day featured an overview of NCIBI, updates on NCIBI activities from its computational science and Driving Biological Projects cores and new and ongoing initiatives with a focus on the upcoming renewal. The afternoon session entitled, "National interactions to drive translation of bioinformatics into CTSA and CaBIG communities" featured perspectives from NCIBI (Brian Athey), i2B2 (Shawn Murphy), and CaGRID (Joel Saltz) and ended with a closing keynote address by Jill Mesirov, Ph.D., Associate Director and Chief Informatics Officer, Broad Institute. Participants had the opportunity to present posters of their work.
Below, you can view videos and download the workshop tutorials as well as download or view other presentations.
Presentations - Tuesday, April 28th
NCIBI offered a "Try Our Tools" workshop that provided an opportunity for the participants to learn about our applications with guided instruction in 4 separate modules. Tutorial booklets based on realistic hands-on cases were provided. Specialists were available to answer questions about applying our tools to the participants' research. Facilitated by technology advances that NCIBI uses to integrate data from diverse sources and heterogeneous formats, the workshop allowed the participants to explore such questions as:
- What proteins interact and in what pathways?
- What compounds and reactions in a pathway may be associated with a set of genes?
- What interactions may play a mechanistic role in a disease?
- What articles are relevant to given genes, interactions or diseases?
- What genes are significantly enriched for a concept or for the same set of concepts?
The tutorials, sample data, and other downloads, and videos of the workshop modules are available online so you can participate in a "Virtual Workshop". Please visit the "Virtual Workshop" link here.
"Cyberinfrastructure support for research, challenges and opportunities for the NCBC program"
Gwen Jacobs, Ph.D.
Professor, Department of Cell Biology and Neuroscience Montana State University
Presentations - Wednesday, April 29th
Karin A. Remington, Ph.D.
Director, Center for Bioinformatics and Computational Biology National Institute of General Medical Sciences, National Institutes of Health
"NCIBI at Year 4:
Where have we been and where are we going--challenges and solutions ahead"
Brian Athey, Ph.D.
Professor, Biomedical Informatics Associate Director, Center for Computational Medicine and Bioinformatics Principal Investigator, NCIBI University of Michigan Medical School
Core 1 & 2 Update:
H.V. Jagadish, Ph.D.
Professor, Electrical Engineering & Computer Science Director, Core 1 & 2, NCIBI University of Michigan
Core 5 Update:
Barbara Mirel, Ph.D.
Associate Research Scientist, School of Education Director, Core 5, NCIBI University of Michigan
Core 4 and 6 Update:
Jim Cavalcoli, Ph.D.
Project Manager, National Center for Integrative Biomedical Informatics Director CCDU Bioinformatics Core, Center for Computational Medicine and Bioinformatics University of Michigan Medical School
Cancer DBP Update:
Gil Omenn, M.D., Ph.D.
Professor, Internal Medicine Director, Center for Computational Medicine and Bioinformatics University of Michigan Medical School
Arul M. Chinnaiyan, M.D., Ph.D.
Investigator, Howard Hughes Medical Institute S.P. Hicks Endowed Professor Professor of Pathology and Urology University of Michigan Medical School
Bipolar DBP Update:
Melvin McInnis, M.D.
Thomas B and Nancy Upjohn Woodworth Professor of Bipolar Disorder and Depression Professor of Psychiatry
Diabetes DBP Update:
Matthias Kretzler, M.D.
Associate Professor, Internal Medicine Research Associate Professor, Computational Medicine and Bioinformatics University of Michigan Medical School
Eva Feldman, M.D., Ph.D.
Russell N. DeJong Professor of Neurology Director, Program for Neurology Research & Discovery
Charles Burant, M.D., Ph.D.
Professor, Molecular & Integrative Physiology University of Michigan Medical School
Bridging NCBCs, CTSAs, and CaBIG; Moderator: Brian Athey
"National interactions to drive translation of bioinformatics into CTSA and CaBIG communities"
NCIBI and NCBCs:
Brian Athey, Ph.D.
-Watch recording (includes below presentations by Shawn Murphy & Joel Saltz)
i2B2 and CTSAs:
Shawn Murphy, M.D., Ph.D.
Assistant Professor of Neurology Medical Director, Research Computing, Partners HealthCare Harvard Medical School
caGRID and CaBIG:
Joel Saltz, M.D., Ph.D.
Director, Center for Comprehensive Informatics, Chief Medical Information Officer, Emory Healthcare, Professor, Department of Pathology Emory School of Medicine.
"Challenges and Paradigms in Computational Genomics"
Jill Mesirov, Ph.D.
Associate Director and Chief Informatics Officer Broad Institute