The National Center for Integrative Biomedical Informatics     

The National Center for Integrative Biomedical Informatics (NCIBI) is one of seven National Centers for Biomedical Computing (NCBC) in the NIH Roadmap. NCIBI is based at the University of Michigan and is part of the UM Center for Computational Medicine and Biology (CCMB). Brian Athey is the Principal Investigator for the NCIBI.

The mission of the National Center for Integrative Biomedical Informatics (NCIBI), founded in October 2005, is to create targeted knowledge environments for molecular biomedical research that help guide experiments and enable new insights from the analysis of complex diseases.
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NIH, the NephCure Foundation and U of M support kidney study

“The kidney community has had a strong interest in this work for a long time, but, until now, we have not had adequate funding for a coordinated effort,” says project director Matthias Kretzler, M.D., professor of internal medicine at the U-M Medical School and a nephrologist at the U-M Health system. - Read Article

Announcing The NCIBI Natural Language Processing Web Service

The NCIBI NLP web services provide programmatic access to parsed and tagged text from the National Library of Medicine's PubMed literature database. The PubMed text is currently tagged by Entrez GeneID, allowing researchers to retrieve text that may be related to genes of interest. Untagged sentence-level parsed text is also available through this interface for inclusion into literature-oriented data pipelines. Future versions will have tags for MeSH terms, compounds, and other biomedically relevant concepts. The NCIBI NLP database is updated on a nightly basis.

For more information along with instructions on accessing the service click here.

NCIBI/RCMI: Workshop on Translational Bioinformatics

Presentations and videos are available from the NCIBI July workshop on translational bioinformatics for various Research Centers in Minority Institutions (RCMI) investigators. Participants received training in the use of NCIBI tools and resources for translational research. They also had the opportunity to learn about other programs at UM and network with UM and other RCMI researchers to build research relationships and collaborations.

To download presentations from the workshop click here.

Read the RTRN.net article about the workshop here.

Recent Publications

Sartor MA, Mahavisno V, Keshamouni VG, Cavalcoli J, Wright Z, Karnovsky A, Kuick R, Jagadish HV, Mirel B, Weymouth T, Athey B, Omenn GS. ConceptGen: a gene set enrichment and gene set relation mapping tool. Bioinformatics. PubMed PMID: 20007254

Richard C McEachin , Nancy L Saccone , Scott F Saccone , Yelena D Kleyman-Smith , Tiara Kar , Rajesh K Kare , Alex S Ade , Maureen A Sartor , James D Cavalcoli and Melvin G McInnis. Modeling complex genetic and environmental influences on comorbid bipolar disorder with tobacco use disorder. BMC Medical Genetics. 2010 January 26;11:14.
- Read Abstract

Recent Presentations

AACR Special Conference on Cancer Epigenetics
San Juan, Puerto Rico, Jan 20-23, 2010

Novel integrative methods identify genes associated with HPV -
"Combined approach using the Illumina Infinium methylation27 beadarray and Affymetrix tiling chip set: Preliminary results illustrate methylation differences in HPV(+) and HPV(-) head and neck cancers" - Maureen Sartor - Read Abstract